Panhandle Plains Vacations from $366

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Your Panhandle Plains Vacation

Panhandle Plains's rugged landscapes and rich traditions are just the beginning of the great things this destination has to offer travelers. Get the best out of your retreat by pulling together your own Panhandle Plains vacation package. Your trip to Panhandle Plains wouldn't be complete without getting to some of its most well-known cities, starting with Amarillo. Two of the top attractions here include Cadillac Ranch and Wonderland Amusement Park. Lubbock is another favorite with Panhandle Plains travelers. Visitors to this exciting destination enjoy Buddy Holly Center and United Supermarkets Arena. Expedia has everything you need when it comes to organizing your Panhandle Plains vacation. From accommodations and flights, to car rentals and activities, we know how to create a travel experience like no other.

The Latest Panhandle Plains vacation packages

Price found within the past 48 hours. Click for updated prices.
Wingate by Wyndham DFW / North Irving
Casa Duro
Element Dallas Downtown East
Hilton Garden Inn Fort Worth / Fossil Creek
Hyatt Place Dallas/North Arlington/Grand Prairie
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Where to stay in Panhandle Plains

Find the best Panhandle Plains areas and neighborhoods for the activities you enjoy most. Learn more about Panhandle Plains

Discover the most popular places to visit in Panhandle Plains

Panhandle Plains Hotel Deals

The Cactus Cove Inn and Suites

The Cactus Cove Inn and Suites

2 out of 5
2501 E Interstate Dr, Amarillo, TX
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Aug 5 to Aug 6
$102 total
Aug 5 - Aug 6
Total includes taxes and fees
7.8/10 Good! (1,844 reviews)
Oshkosh day 3
"Second time to stay here. Great room, staff and location"

Reviewed on Jul 30, 2025

The Cactus Cove Inn and Suites
La Quinta Inn by Wyndham Amarillo Mid-City

La Quinta Inn by Wyndham Amarillo Mid-City

3 out of 5
1708 I-40 E, Amarillo, TX
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $64 total per night from Sep 2 to Sep 3
$64 total
Sep 2 - Sep 3
Total includes taxes and fees
7.2/10 Good! (1,103 reviews)
"Great motel for the price. The fitness room was down which was disappointing. Room and staff made up for that. Breakfast was good as well. I’d stay here again"

Reviewed on Aug 2, 2025

La Quinta Inn by Wyndham Amarillo Mid-City
Atrea Inn Amarillo

Atrea Inn Amarillo

2.5 out of 5
2035 Paramount Blvd, Amarillo, TX
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $74 total per night from Aug 5 to Aug 6
$74 total
Aug 5 - Aug 6
Total includes taxes and fees
8.4/10 Very Good! (2,074 reviews)
"Room was nice and clean. Parking was convenient. Nice outside recreational/lounging area. Breakfast included in the lobby. Overall great value for the money."

Reviewed on Aug 1, 2025

Atrea Inn Amarillo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.