Panhandle Plains Vacations from $258

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Your Panhandle Plains Vacation

Panhandle Plains's rugged landscapes and rich traditions are just the beginning of the great things this destination has to offer travelers. Get the best out of your retreat by pulling together your own Panhandle Plains vacation package. Your trip to Panhandle Plains wouldn't be complete without getting to some of its most well-known cities, starting with Amarillo. Two of the top attractions here include Cadillac Ranch and Wonderland Amusement Park. Lubbock is another favorite with Panhandle Plains travelers. Visitors to this exciting destination enjoy Buddy Holly Center and United Supermarkets Arena. Expedia has everything you need when it comes to organizing your Panhandle Plains vacation. From accommodations and flights, to car rentals and activities, we know how to create a travel experience like no other.

The Latest Panhandle Plains vacation packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Fort Worth / Fossil Creek
Cooper Hotel Conference Center & Spa
Luxury Downtown Dallas Stay by Amyfinehouse
Hilton Fort Worth
Hampton Inn & Suites Dallas-The Colony, TX
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Where to stay in Panhandle Plains

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Panhandle Plains Hotel Deals

Baymont by Wyndham Amarillo East

Baymont by Wyndham Amarillo East

2.5 out of 5
1700 I-40 E, Amarillo, TX
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $71 total per night from Aug 25 to Aug 26
$71 total
Aug 25 - Aug 26
Total with taxes and fees
8.4/10 Very Good! (1,590 reviews)
"We liked the clean rooms, friendly staff, parking and close walking distance t o Denny's."

Reviewed on Aug 20, 2025

Baymont by Wyndham Amarillo East
The Cactus Cove Inn and Suites

The Cactus Cove Inn and Suites

2 out of 5
2501 E Interstate Dr, Amarillo, TX
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $102 total per night from Aug 25 to Aug 26
$102 total
Aug 25 - Aug 26
Total with taxes and fees
7.8/10 Good! (1,900 reviews)
Fantastic stay!
"This place is so incredible. The rooms are big, fully stocked, and amazingly clean and comfortable. They also have a great hot breakfast, a pool, a nice clothing store with many needed accessories, a fun interior with games for adults and kids, a beautiful wishing well with koi, and a full bar. What ..."

Reviewed on Aug 18, 2025

The Cactus Cove Inn and Suites
Holiday Inn Express & Suites Amarillo West by IHG

Holiday Inn Express & Suites Amarillo West by IHG

2.5 out of 5
8330 W Amarillo Blvd, Amarillo, TX
Fully refundable
$100 nightly
The price is $115 total per night from Sep 24 to Sep 25
$115 total
Sep 24 - Sep 25
Total with taxes and fees
9.2/10 Wonderful! (1,789 reviews)
"Nice rooms and property. Dog friendly."

Reviewed on Aug 23, 2025

Holiday Inn Express & Suites Amarillo West by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.